Liam Williams ruled out of World Cup semi-final match against South Africa
Liam Williams will miss Wales' semi-final clash against South Africa on Sunday after suffering an ankle injury in training.
The full-back will also miss the final if Wales beat South Africa on Sunday.
Leigh Halfpenny will feature at full-back instead of Williams against the Springboks, and centre Jonathan Davies has been named in the team after recovering from a knee injury that sidelined him for last weekend's quarter-final victory over France.
Davies replaces Owen Watkin, lining up alongside Hadleigh Parkes in midfield, while in a third charge, number eight Ross Moriarty takes over from Josh Navidi.
Navidi suffered a hamstring injury in the France game, and had already been ruled out of the rest of the tournament.
The loss of 63 times-capped Saracens star Williams - arguably the northern hemisphere's finest attacking full-back - is a huge blow for Wales head coach Warren Gatland.
''He is undoubtedly a big loss from an attacking perspective,'' Gatland said.
''Bringing in the experience of someone like Leigh Halfpenny gives us a different element. I think defensively he's probably the best full-back in the world.''
Gatland is confident Wales can make that all important World Cup final.
''When you want something bad enough, when you really really want it, it can happen.''
The experienced Halfpenny has made one start in the tournament - against final pool stage opponents Uruguay - and went on as a replacement against Georgia.
Meanwhile, scrum-half Gareth Davies will win his 50th cap, partnering Dan Biggar at half-back in Yokohama.
Gatland retains the same front-five that has served him well during the tournament, with skipper Alun Wyn Jones making his 142nd Test appearance for Wales and the Lions.
That puts him level with Italy captain Sergio Parisse on international rugby's all-time appearance chart, just six Tests behind New Zealand World Cup-winning skipper Richie McCaw.