A woman has been killed as around 20 vehicles were involved in a major crash when roads became treacherous due to thick fog.
The A40 was closed in both directions due to the multi-vehicle crash, which stretched for more than half a mile near Witney in Oxfordshire, the ambulance service said.
A severe weather warning for fog has been reissued after multiple traffic collisions on the A40.
Motorists are being warned that freezing fog patches will become more widespread and locally dense Wednesday evening until Thursday lunchtime.
The Met Office said: "Driving conditions will be difficult with journeys likely to take longer than usual whilst some delays to air travel are possible."
The yellow warning, which means "beware", was issued for the whole of England, with the exception of the most western and northern points.
The Democratic presidential candidate may also have shown his cards on his choice of running mate.
The US president also shared a post on Twitter accusing Dr Anthony Fauci of misleading the public over hydroxychloroquine.
Fears over an impending second wave of coronavirus dominates Wednesday’s front pages.