England are set to play Uruguay at 8pm in a match that has lost a good deal of its allure for Lions fans since the host's defeat by Australia.
Meanwhile Scotland, looking to secure their place in the quarter finals, play Samoa at St James Park at 2.30pm, and Wales play Australia in Twickenham, kicking off at 4.45pm.
Large numbers of England fans will be backing Wales now that their team is heading out of the Rugby World Cup, according to a survey commissioned by bookmaker William Hill.
Of those surveyed, 24% said they would be following Wales for the rest of the tournament.
England are due to play Uruguay in Manchester late on Saturday, in what will be their final match of the 2015 Rugby World Cup, but the fixture has lost much of its appeal for fans since England's defeat by Australia.
Wales, meanwhile, are due to play Australia at Twickenham at 4.45pm, and appear able to rely on a good deal of support from England fans.
Change is needed in the England camp after a disastrous Rugby World Cup - but perhaps England's head coach should get a second chance.
The Rugby Football Union has ruled out any "hasty reaction" after England were knocked out of the Rugby World Cup by Australia.
The girlfriend of England rugby captain Chris Robshaw says she has been the target of abuse since the defeat to Wales last weekend.