World powers and Iran have formally announced a comprehensive nuclear accord.
Federica Mogherini, the European Union's foreign policy chief, said: "Today is an historic day."
She added that it was a great honour "for us to announce that we have reached an agreement on the Iranian nuclear issue".
Iranians took to the streets of Iran this evening to celebrate after the country signed an historic deal to lift sanctions in exchange for halting its nuclear programme.
In the more affluent north of the capital, young crowds chanted and clapped, while some held aloft pictures of Iranian foreign minister Mohammad Javad Zarif and President Hassan Rouhani.
One person, a university student said: "I feel a little lighter from all that tough work. Thank you Dr. Rouhani and thank you Dr. Zarif."
The deal is set to end years of economic hardship for Iran, which over the past three years has been stripped of access to the international financial system, making it hard to sell oil and pay for imports.
Prime minister Netanyahu has likened the nuclear deal with Iran to the unsuccessful 1994 deal on North Korea's nuclear programme.
An end to Iranian nuclear question could soon be a reality after years of hard and often tense negotiations.