David Cameron - the first Conservative leader to win an outright majority for 23 years - named his ministerial team.
Sajid Javid took the job of Business Secretary and Boris Johnson was handed a non-ministerial role while he remains Mayor of London.
A number of female MPs, including Priti Patel and Amber Rudd, were also promoted to leading positions.
Business Secretary Vince Cable, Treasury Secretary Danny Alexander, former leader Charles Kennedy and Simon Hughes all fell, while at one point it looked like Nick Clegg himself would be toppled.
In all, it was a terrible night for the Liberal Democrats.
ITV News Political Correspondent Emily Morgan reports:
It was one of the last big Cabinet jobs to be announced but the Prime Minister has chosen to stick with Jeremy Hunt as Health Secretary.
Prime Minister David Cameron has today continued to put together his new cabinet. Here is what the new-look cabinet looks like so far.
David Cameron was unsurprisingly in a great mood as he spoke to journalists before addressing his 331 Conservative MPs today.