Afghanistan's Independent Election Commission said initial results based on 10 percent of the vote from 26 out of 34 provinces showed former opposition leader Abdullah Abdullah in the lead with 41.9 percent.
NATO's Secretary General congratulated the Afghan people after millions turned out to vote in an historic election.
Anders Fogh Rasmussen said in a statement: "The Afghan people can be proud of their security forces, who have done an outstanding job in securing the elections [...] This has truly been an election led by Afghans, secured by Afghans, for the future of Afghans."
The Democratic presidential candidate may also have shown his cards on his choice of running mate.
The US president also shared a post on Twitter accusing Dr Anthony Fauci of misleading the public over hydroxychloroquine.
Fears over an impending second wave of coronavirus dominates Wednesday’s front pages.