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Protein 'fights cholesterol drugs'

Cholesterol-lowering drugs taken by millions of people may sometimes not work effectively because of a protein secreted by fat tissue, say scientists.

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Liver's ability reduced to clear 'bad' cholesterol

Research into the effect of protein on cholesterol-lowering drugs also showed that resistin increases the production of LDL in human liver cells, and reduced the liver's ability to clear "bad" cholesterol out of the body.

The protein accelerated the accumulation of LDL in arteries, leading to a narrowing of the blood vessels and an increased risk of heart disease.

The possibilities for improved therapy for the causes of cardiovascular disease are very important.

Fortunately, we know a great deal about heart disease prevention and how to reverse some of the risks.

She urges people to monitor their weight and waist size, eat nutritious, low-fat food, and be physically active.

– Dr Beth Abramson, from the Heart and Stroke Foundation of Canada

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