The North East and North Yorkshire has voted overwhelmingly to leave the EU with only Newcastle, Harrogate and York voting to remain.
See what politicians, businesses and organisations are saying in the wake of the UK exiting the EU
Northern Powerhouse Minister James Wharton has expressed his disappointment at Boris Johnson's decision to pull out of the race for the Conservative Party leadership.
The Stockton South MP said yesterday's announcement was disappointing as Mr Johnson had given him assurances regarding the future of the party and Britain after its exit from the European Union.
Mr Wharton said he would be speaking to all the party's leadership candidates before deciding who to back.
"I would personally like to thank the local community for their amazing donations of food, toiletries and clothing. "
Owners John and Irene Hays say there is ''light at the end of the tunnel'', after the pandemic forced them to close 650 UK stores.
There has been resistance to calls to dismantle memorials to the explorer.