The North East and North Yorkshire has voted overwhelmingly to leave the EU with only Newcastle, Harrogate and York voting to remain.
See what politicians, businesses and organisations are saying in the wake of the UK exiting the EU
The Bishop of Newcastle has called on people to unite, to heal divisions highlighted by the EU referendum.
The Right Revd Christine Hardman says communities should work together to build a country she describes as 'generous, outward facing and welcoming'.
The Bishop told ITV News Tyne Tees that she was saddened by the nature of the debate on both sides at points during the campaign. In its aftermath, she hopes people can look to what they have in common.
Watch the Bishop's comments here:
"I would personally like to thank the local community for their amazing donations of food, toiletries and clothing. "
Owners John and Irene Hays say there is ''light at the end of the tunnel'', after the pandemic forced them to close 650 UK stores.
There has been resistance to calls to dismantle memorials to the explorer.