The North East and North Yorkshire has voted overwhelmingly to leave the EU with only Newcastle, Harrogate and York voting to remain.
See what politicians, businesses and organisations are saying in the wake of the UK exiting the EU
The North East must not lose out as a result of Britain's exit from the European Union, according to the Shadow Europe Minister.
Pat Glass, Labour MP for North West Durham, had campaigned to Remain in the EU and now says the 'Leave' camp need to deliver on guarantees it given to the region during the referendum.
Mrs Glass told ITV News:
"I would personally like to thank the local community for their amazing donations of food, toiletries and clothing. "
Owners John and Irene Hays say there is ''light at the end of the tunnel'', after the pandemic forced them to close 650 UK stores.
There has been resistance to calls to dismantle memorials to the explorer.