The North East and North Yorkshire has voted overwhelmingly to leave the EU with only Newcastle, Harrogate and York voting to remain.
See what politicians, businesses and organisations are saying in the wake of the UK exiting the EU
Anne-Marie Trevelyan MP (Berwick-upon-Tweed) has told ITV Tyne Tees that she expects Boris Johnson to put his name forward to be the next Prime Minister.
David Cameron announced he is to resign as Prime Minister and that a new leader will be named by October.
"I would personally like to thank the local community for their amazing donations of food, toiletries and clothing. "
Owners John and Irene Hays say there is ''light at the end of the tunnel'', after the pandemic forced them to close 650 UK stores.
There has been resistance to calls to dismantle memorials to the explorer.