Addenbrooke's Hospital in Cambridge became the latest hospital to activate a major incident plan to cope with the surge in demand.
The hospital says it has been under extreme pressure for the past two days and has been in critical internal incident mode.
However as of 7pm last night the hospital declared a major incident.
The hospital says all non-emergency surgery and procedures have been cancelled as part of the plan to manage demand for services.
Click below to watch our report from Matthew Hudson