Boy, 5, 'who lives in a bubble' calls for supporters to wear yellow

A five-year-old boy who 'lives in a bubble' after being born without an immune system has made a touching video urging people to support him by wearing his favourite colour yellow.

Seth Lane, from Corby, Northamptonshire, has lived in a sterile germ-free environment for more than half of his life after being diagnosed with severe combined immunodeficiency.

Known as 'bubble boy disease', the condition is caused by a mutated gene and means the body's antibodies can't respond to infections, leaving sufferers extremely vulnerable to germs.

Seth is due to undergo a second bone marrow transplant after the first one was unsuccessful and has issued a video plea for supporters to wear yellow to know they are thinking of him.

The youngster, who uses speech cards in the video filmed by dad Nik, urges people to post pictures of themselves wearing yellow to Facebook, Twitter or Instagram with #wearyellowforseth on March 27.

The video was posted on a blog called Our Little Hero which was set up by his parents.

In the video, a smiling Seth perched on his hospital bed, says: "Hello I'm Seth. I'm five-years-old and I love Fireman Sam, Paw Patrol and yellow.

"I'm in hospital, I was born with no immune system, and I need a second bone marrow transplant.

"On 27th March lots of people are going to wear yellow to show me how much support I have. Are you going to join in?"

"Post a picture of you wearing yellow to Facebook, Twitter or Instagram with #wearyellowforseth."

His parents will put the pictures up in his room.

After his first bone marrow transplant, Seth was unable to go to nursery or play outside in parks.

Mother Leanne said: "He had no contact with other children until he was two-and-a-half. We would go out in the pram and I would have to put the rain cover over him with a little fan inside - people probably thought I was mad."

He finally started school and made friends when he fell ill again and doctors found his own cells had turned on him.

Since January, the youngster has returned to hospital where he will have a second transplant once he is well enough for the operation.

Watch Seth's full video below: