England are set to play Uruguay at 8pm in a match that has lost a good deal of its allure for Lions fans since the host's defeat by Australia.
Meanwhile Scotland, looking to secure their place in the quarter finals, play Samoa at St James Park at 2.30pm, and Wales play Australia in Twickenham, kicking off at 4.45pm.
Ireland play Canada at Cardiff's Millennium Stadium as both team's look to start their Rugby World Cup 2015 campaigns.
The match kicks off at 2.30pm and is live on ITV.
On Friday night England and Fiji kicked off proceedings at Twickenham in a stop-start match which saw the hosts win, 35-11.
Change is needed in the England camp after a disastrous Rugby World Cup - but perhaps England's head coach should get a second chance.
The Rugby Football Union has ruled out any "hasty reaction" after England were knocked out of the Rugby World Cup by Australia.
The girlfriend of England rugby captain Chris Robshaw says she has been the target of abuse since the defeat to Wales last weekend.