The head of the new full-scale Metropolitan Police inquiry into the disappearance of Madeleine McCann has said there are 38 persons of interest, including 12 British nationals, that they want to speak to. He says they believe she is still alive.
Metropolitan Police Detective Chief Inspector Andy Redwood has said told ITV News that moving from a review to an investigation in the Madeleine McCann case was "an important moment" for the missing girl.
He said drawing together the material obtained by Scotland Yard, Portuguese authorities and private investigators had increased their investigative leads from 195 to over 3,800.
Police believe Madeleine could still be alive, and they have drawn up a list of 38 people - 12 of them British - who they want to speak to.
What happened to Madeleine? It is likely only one person knows the answer, and finding that person is the focus of a British investigation.
The Met Police said there are 38 people of interest in the Madeleine McCann case. Here is a timeline of the key events in her disappearance.