The planning application for the controversial Coventry Gateway scheme has been rejected.
The plans for a major technology park on green belt land near Coventry Airport were put forward several years ago.
Supporters said the site would generate thousands of jobs, but local campaigners lodged strong objections.
After months of delays, Communities Secretary Eric Pickles has rejected the application.
The multi-million pound Coventry Gateway development which would have created thousands of jobs has been rejected by the government.
Eric Pickles, the Secretary of State for Communities and Local Government, turned down plans to develop the 700 acre site around Coventry Airport, that could have created up to 10,000 jobs.
The Coventry and Warwickshire Gateway plans aimed to develop an area of 741 acres to the north, east and south of Coventry airport. Plans for the development included a major new technology and manufacturing and distribution park.
The decision has been criticised by Coventry City Council’s Cabinet Member for Business, Enterprise and Employment, Kevin Maton.
Meanwhile Geoffrey Robinson, the MP for Coventry North West, said: “I’m hugely disappointed by this decision.
"This development had the prospect of attracting thousands of jobs into our city, this is a real slap in the face for our City.”
West Midlands Weather: Windy on Sunday with showers and sunny spells
East Midlands Weather: Heavy rain over Derbyshire hills, drier and brighter elsewhere
The city’s spike in coronavirus cases has sparked a report that it may be the first UK location to be subjected to a district lockdown.